CEO: Tyler Wanke, MD

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Madison Scientific, Inc.

Smart, connected innovation transforming hydrocephalus care.

Overview
Madison Scientific is redefining the standard of care for patients with hydrocephalus through intelligent, connected innovation. Its flagship SmartShunt™ system combines advanced pressure regulation, continuous intracranial pressure monitoring, and AI-driven analytics to predict and prevent complications before they occur.

The Challenge
Hydrocephalus affects millions worldwide and remains one of the most common conditions treated by neurosurgeons. Yet the shunts used to manage it fail at alarming rates—often within the first year—leading to repeat surgeries, hospitalizations, and emotional and financial strain for patients and families.

The Solution
Madison Scientific’s SmartShunt™ system addresses the root cause of shunt failure: over-drainage and blockage. By integrating precision valve control, real-time pressure data, and predictive algorithms, the system empowers clinicians with insights to intervene early and manage care proactively. This approach not only improves outcomes but reduces avoidable costs and expands access to equitable, high-quality neurosurgical care.

Why It Matters
Hydrocephalus is a lifelong condition. Madison Scientific’s innovation shifts care from reactive to proactive—helping patients live with stability, confidence, and fewer hospital visits. For clinicians, it delivers actionable intelligence and peace of mind. For health systems, it means lower costs and better outcomes.

CIF Investment Focus
Catalytic Impact Foundation invested in Madison Scientific as part of our Precision Health Systems focus—supporting technologies that move healthcare from treatment to prevention. Madison Scientific exemplifies this vision through its fusion of engineering, data, and empathy-driven design to build a smarter, more sustainable future for brain health.