NEW YORK, Sept. 21, 2025 — One breakthrough can save a life. But a catalytic chain of them? That changes everything.

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At CGI 2025, Catalytic Impact Foundation Fuels a Network of Innovation—From Brain Circuits to Rare Diseases to Delivery Rooms

NEW YORK, Sept. 21, 2025 — One breakthrough can change a life. But a catalytic chain of potential breakthroughs? That changes everything.

Picture a physician finally able to show patients exactly how their brain circuits respond to treatment. Ceretype Neuroscience (🌐 https://ceretype.com) delivers those insights. With advanced imaging that maps the brain in real time, Ceretype replaces guesswork with precision—helping to advance psychiatry and neurology into a new era (Ceretype, 2024).

From their first breath, a newborn with congenital heart disease faces a fragile beginning. Starlight Cardio (🌐https://www.starlightcardio.com) creates tiny, donut-shaped supports and soft valves that guide blood flow as it should—delivered through a thin tube instead of open surgery. Built to adapt as children grow, therefore reducing subsequent surgeries, these innovations give the most vulnerable babies a real chance to survive and thrive.

Decades between, yet more connected than they seem. Cleerly Health (🌐 https://cleerlyhealth.com) turns heart scans into precise digital maps, revealing cardiovascular disease sooner and guiding smarter care before heart attacks strike. By targeting the world’s leading cause of death—especially in aging populations—Cleerly helps shift care from crisis response to prevention.

Whether the brain, the heart, young, or old, these stories share more than science. They reveal how breakthroughs across decades and disciplines are connected through a single thread—regenerative philanthropy.

Richard Lipkin, CIF Founder, highlights:
“Today’s profits fund tomorrow’s innovation. Today’s successes become tomorrow’s seeds, in a perpetual cycle of regenerative, self-sustaining innovation. We accelerate science out of the lab and to the bedside of patients—and then do it again. We fund forward.”

⚙️ We Move Early—And We Keep Building

Potential breakthroughs don’t stall because they lack potential. They stall because no one shows up early enough to support what’s possible. At the Catalytic Impact Foundation (CIF), we do.

CIF makes equity investments—not grants—at the moment bold science needs validation. We pair capital with strategic guidance and supportive partnership. Then we recycle outcomes: the profits from every successful exit flows back into our evergreen fund, powering the next wave of solutions.

🚀 Why It Works

Rachel Butler, CIF President, explains:
“We combine the discipline of venture with the purpose of philanthropy. Early investment de-risks the science, attracts follow-on funding, and accelerates the path from lab bench to bedside. That flywheel—Regenerative Philanthropy—turns each success into fuel to accelerate the next potential breakthrough.”
She continues:
“There are powerful healthcare solutions being developed every day. But most don’t make it out of the lab. We back the breakthroughs others won’t—making sure the patient is always the the priority.”
Rob Wolk, CIF Chair, stresses:
“CIF’s innovative model provides the special sauce - the critical capital, expertise and support for founders, that de-risks early-stage companies and ensures key therapeutics and solutions make it into the hands of patients.”

📊 Proof That It Works

50+ companies funded
52% women-led (vs. <3% industry average)
24 technologies commercialized
8 successful exits
$900M+ in follow-on capital unlocked
2.7M lives potentially saved
148M lives potentially improved

One of the missing ingredients in moving science into the real world is visibility. Egal Pads (🌐https://www.egalpads.com) proves the point. Egal was the winner of the Mass Innovation Health Tech Award (2024), is a current Finalist in Fast Company’s Innovation by Design Awards, and has one many industry innovation awards! Egal makes menstrual products as accessible as toilet paper—already in thousands of schools and now expanding to airports, stadiums, and public spaces nationwide. The impact is immediate: expanded access for those in need, fewer missed classes, no whispered shame, and a generation of girls and women who no longer have to choose between dignity and participation.

🌍 At CGI and Beyond: Scaling the Model That Works

From brain circuits to newborn hearts to the silent risks of cardiovascular disease, the unmet health needs are everywhere—and too often, they cost lives. Innovation stalls without strategic early funding, and patients fall through the cracks. Here, CIF’s regenerative model proves its value: bold innovations—with one success feuling the next

Improving maternal health is a strong priority for CIF. The U.S. ranks 29th in maternal mortality among developed nations, with 80% of deaths considered preventable (World Health Organization, 2023; Centers for Disease Control and Prevention, 2023). That’s why CIF is accelerating technologies that:

Developing a third-trimester blood test to predict the risk of postpartum depression, (Dionysis Health 🌐https://dionysushealth.com)
Reimagine maternal-fetal monitoring (Raydiant Oximetry 🌐 https://raydiantoximetry.com)
Expand access to doula care from early pregnancy through postpartum (Flourish Care 🌐https://flourishcommunitycare.com)
Provide holistic mental health support across all stages of a women’s life, but focusing on pregnancy through postpartum (LunaJoy Health 🌐 https://hellolunajoy.com)

But maternal health is only one frontier. At CGI 2025, CIF will showcase how its regenerative philanthropy model is scaling across six health verticles where patients can’t wait: women’s health, brain and mental health, rare disease, children’s health, aging, and healthcare access. CIF scales what works: early capital to address the “Valley of Death”, expert partnership that speeds development, and a funding-forward model that reinvests the profits from every success. The results compound—evidence arrives sooner, adoption accelerates, and access expands.

CIF’s model has been created as a platform to accelerate much-needed healthcare solutions, through funding, sharing expertise, and developing partnerships with like-minded organizations. Our commitment is to expand and scale—because patients can’t wait.

About the Catalytic Impact Foundation

The Catalytic Impact Foundation (CIF) is a 501(c)(3) nonprofit that funds early-stage healthcare solutions for the world’s most urgent and overlooked challenges. CIF is distinct in its regenerative philanthropy model: unlike traditional philanthropy, every success is reinvested to seed future breakthroughs. By combining the rigor of venture investment with the mission of philanthropy, CIF accelerates science from lab bench to bedside—ensuring bold innovations don’t stall in early stages but reach the people who need them most.

🌐 www.cifimpact.org | 📧 press@cifimpact.org

We regenerate every success into the breakthroughs ahead.